Sex-specific effects of microglial activation on Alzheimer’s disease proteinopathy in older adults. Casaletto KB, Nichols E, Aslanyan V, Simone SM, Rabin JS, LaJoie R, Brickman AM, Dams-O’Connor K, Palta P, Kumar RG, George KM.  Brain. 2022 Jul 23.

Pa J, Aslanyan V, Casaletto KB, RenterÃa MA, Harrati A, Tom SE, Armstrong N, Rajan K, Avila-Rieger J, Gu Y, Schupf N. Effects of Sex, APOE4, and Lifestyle Activities on Cognitive Reserve in Older Adults. Neurology. 2022 Jul 20.Pa 2022


Simultaneous Exercise and Cognitive Training in Virtual Reality Phase 2 Pilot Study: Impact on Brain Health and Cognition in Older Adults. Sakhare A, Stradford J, Ravichandran R, et al. Brain Plasticity. 2021;7(2):111-130. Sakhare, et al 2021

Conducting a VR Clinical Trial in the Era of COVID-19.  Stradford J, Sakhare A, Ravichandran R, Schroeder ET, Michener LA, Pa J. Frontiers in Virtual Reality. 2021 Apr 29;2:639478. Stradford, et al 2021

Early neuroinflammation is associated with lower amyloid and tau levels in cognitively normal older adults. Albrecht DS, Sagare A, Pachicano M, et al.  Brain, Behavior and Immunity. 2021;94:299-307. Albrecht, et al 2021


Associations between vascular function and tau PET are associated with global cognition and amyloid. Albrecht D, Isenberg AL, Stradford J, Monreal T, Sagare A, Pachicano M, Sweeney M, Toga A, Zlokovic B, Chui H, Joe E.  Journal of Neuroscience.2020 Oct 12. PDF

Exploratory analysis of mtDNA haplogroups in two Alzheimer’s longitudinal cohorts. Swerdlow RH, Hui D, Chalise P, Sharma P, Wang X, Andrews SJ, Pa J, Mahnken JD, Morris J, Wilkins HM, Burns JM. Alzheimer’s & Dementia. 2020 Jun 16. PDF

APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline. Montagne A, Nation DA, Sagare AP, Barisano G, Sweeney MD, Chakhoyan A, Pachicano M, Joe E, Nelson AR, D’Orazio LM, Buennagel DP. Nature. 2020 May;581(7806):71-6. PDF

Mitonuclear interactions influence Alzheimer’s disease risk.Andrews SJ, Fulton-Howard B, Patterson C, McFall GP, Gross A, Michaelis EK, Goate A, Swerdlow RH, Pa J, Alzheimer’s Disease Neuroimaging Initiative.  Neurobiology of Aging. 2020 Mar 1;87:138-e7. PDF

Functional connectivity among brain regions affected in Alzheimer’s disease is associated with CSF TNF-α in APOE4 carriers. Contreras JA, Aslanyan V, Sweeney MD, Sanders LM, Sagare AP, Zlokovic BV, Toga AW, Han SD, Morris JC, Fagan A, Massoumzadeh P.  Neurobiology of Aging. 2020 Feb 1;86:112-22. PDF

Late-life physical and cognitive activities independently contribute to brain and cognitive resilience. Casaletto KB, Rentería MA, Pa J, Tom SE, Harrati A, Armstrong NM, Rajan KB, Mungas D, Walters S, Kramer J, Zahodne LB. Journal of Alzheimer’s Disease. 2020. PDF


Cycling and spatial navigation in an enriched, immersive 3D virtual park environment: A feasibility study in younger and older adults.  Sakhare A,  Yang V, Stradford J, Tsang I, Ravichandran R, Pa J.  Frontiers in Aging Neuroscience 2019; 11: 218. PDF

Mitochondria and Alzheimer’s: Is PTCD1 the Smoking Gun? Pa J, Andrews SJ, Swerdlow RH. Trends in Neuroscience. 2019 Nov 1;42(11):759-62. PDF

APOE ɛ4 Gene Dose and Sex Effects on Alzheimer’s Disease MRI Biomarkers in Older Adults with Mild Cognitive Impairment. Hobel Z, Isenberg AL, Raghupathy D, Mack W, & Pa J.  Journal of Alzheimer’s Disease. 2019 Jan 1;71(2):647-58. PDF

Assessing Test-Retest Reliability of Phase Contrast MRI for Measuring Cerebrospinal Fluid Flow Dynamics in Alzheimer’s Disease. Sakhare, A., Barisano, G., & Pa, J. Magnetic Resonance in Medicine. 2018: P3-183. PDF

Vascular dysfunction – The disregarded partner of Alzheimer’s disease. Sweeney, MD, Montagne, A, Sagare, AP, Nation, DA, Schneider, LS, Chui, HC, Harrington, MG, Pa, J, Law, M, Wang, JJ, et al. Alzheimer’s & Dementia. 2019 Jan;15(1):158-167. PDF


Impairment of memory generalization in preclinical autosomal dominant Alzheimer’s disease mutation carriers.  Petok JR, Myers CE, Pa J, Hobel Z, Wharton DM, Medina LD, Casado M, Coppola G, Gluck MA, & Ringman JM. Neurobiology of Aging. 2018 May 1;65:149-57. PDF


Apolipoprotein E genotype and sex risk factors for Alzheimer disease: a meta-analysis.  Neu SC, Pa J, Kukull W, Beekly D, Kuzma A, Gangadharan P, Wang LS, Romero K, Arneric SP, Redolfi A, & Orlandi D. JAMA Neurology. 2017 Oct 1;74(10):1178-89. PDF

A novel PSEN1 (S230N) mutation causing early-onset Alzheimer’s Disease associated with prosopagnosia, hoarding, and Parkinsonism.  Ringman JM, Casado M, Van Berlo V, Pa J, Joseph-Mathurin N, Fagan AM, Benzinger T, Bateman RJ, & Morris JC. Neuroscience Letters. 2017 Sep 14;657:11-5. PDF


Predictive big data analytics: A study of Parkinson’s disease using large, complex, heterogeneous, incongruent, multi-cource and incomplete observations. Dinov ID, Heavner B, Tang M, Glusman G, Chard K, Darcy M, Madduri R, Pa J, Spino C, Kesselman C, Foster I, Deutsch EW, Price ND, Van Horn JD, Ames J, Clark K, Hood L, Hampstead BM, Dauer W, & Toga AW. PLoS One. 2016 Aug 5;11(8). PDF

Brain imaging of neurovascular dysfunction in Alzheimer’s disease. Montagne A, Nation DA, Pa J, Sweeney MD, Toga AW, & Zlokovic BV. Acta Neuropathologica. 2016 May; 131(5):687-707. PDF


Vascular plasticity and cognition during normal aging and dementia. Montagne A, Pa J, & Zlokovic B. JAMA Neurology. 2015 May; 72(5):495-6. PDF


Effect of exercise and cognitive activity on self-reported sleep quality in community-dwelling older adults with cognitive complaints: a randomized controlled trial. Pa J, Goodson W, Bloch A, King AC, Yaffe K, & Barnes DE. Journal of American Geriatrics Society. 2014 Dec; 62(12):2319-26. PDF

Flavanol-rich food for thought. Pa J & Gazzaley A. Nature Neuroscience. 2014 Nov 21; 17(12):1624-5. PDF

The functional oculomotor network and saccadic cognitive control in healthy elders. Pa J, Dutt S, Mirsky JB, Heuer HW, Keselman P, Kong E, Trujillo A, Gazzaley A, Kramer JH, Seeley WW, Miller BL, & Boxer AL. Neuroimage. 2014 Jul 15; 95:61-8. PDF

Reliability measures of functional magnetic resonance imaging in a longitudinal evaluation of mild cognitive impairment. Zanto TP, Pa J, & Gazzaley A. Neuroimage. 2014 Jan 1; 84:443-52. PDF

Cholinergic enhancement of functional networks in older adults with mild cognitive impairment. Pa J, Berry AS, Compagnone M, Boccanfuso J, Greenhouse I, Rubens MT, Johnson JK,  Gazzaley A. Annals of Neurology. 2013 Jun; 73(6):762-73. PDF

Longitudinal change in neuropsychological performance using latent growth models: a study of mild cognitive impairment. Johnson JK, Gross AL, Pa J, McLaren DG, Park LQ,  Manly JJ. Brain Imaging & Behavior. 2012 Dec; 6(4):540-50. PDF


Confirmatory factor analysis of the ADNI Neuropsychological Battery. Park LQ, Gross AL, McLaren DG, Pa J, Johnson JK, Mitchell M,  Manly JJ. Brain Imaging & Behavior. 2012 Dec; 6(4):528-39. PDF

Cortical signatures of cognition and their relationship to Alzheimer’s disease. Gross AL, Manly JJ, Pa J, Johnson JK, Park LQ, Mitchell MB, Melrose RJ, Inouye SK, & McLaren DG. Brain Imaging & Behavior. 2012 Dec; 6(4):584-98. PDF


Baseline predictors of clinical progression among patients with dysexecutive mild cognitive impairment. Johnson JK, Pa J, Boxer AL, Kramer JH, Freeman K, & Yaffe K. Dementia & Geriatric Cognitive Disorders. 2010; 30(4):344-51. PDF

Gray matter correlates of set-shifting among neurodegenerative disease, mild cognitive impairment, and healthy older adults. Pa J, Possin KL, Wilson SM, Quitania LC, Kramer JH, Boxer AL, Weiner MW, & Johnson JK. Journal of International Neuropsychological Society. 2010 Jul; 16(4):640-50. PDF


Patterns of cerebral hypoperfusion in amnestic and dysexecutive MCI. Chao LL, Pa J, Duarte A, Schuff N, Weiner MW, Kramer JH, Miller BL, Freeman KM, &  Johnson JK. Alzheimer Disease & Associated Disorders. 2009 Jul-Sep; 23(3):245-52. PDF

Rule violation errors are associated with right lateral prefrontal cortex atrophy in neurodegenerative disease. Possin KL, Brambati SM, Rosen HJ, Johnson JK, Pa J, Weiner MW, Miller BL, & Kramer JH. Journal of International Neuropsychological Society. 2009 May; 15(3):354-64. PDF

Clinical-neuroimaging characteristics of dysexecutive mild cognitive impairment. Pa J, Boxer A, Chao LL, Gazzaley A, Freeman K, Kramer J, Miller BL, Weiner MW, Neuhaus J, & Johnson JK. Annals of Neurology. 2009 Apr; 65(4):414-23. PDF


Neural organization of linguistic short-term memory is sensory modality-dependent: evidence from signed and spoken language. Pa J, Wilson SM, Pickell H, Bellugi U, & Hickok G. Journal of Cognitive Neuroscience. 2008 Dec; 20(12):2198-210. PDF

Bilateral capacity for speech sound processing in auditory comprehension: evidence from Wada procedures. Hickok G, Okada K, Barr W, Pa J, Rogalsky C, Donnelly K, Barde L, & Grant A. Brain & Language. 2008 Dec; 107(3):179-84. PDF

A parietal-temporal sensory-motor integration area for the human vocal tract: evidence from an fMRI study of skilled musicians. Pa J & Hickok G. Neuropsychologia. 2008 Jan 15; 46(1):362-8. PDF